Nature Portfolio
Prepare your manuscript for Nature Medicine.
Review the checklist, choose your article type, and turn your draft into a cleaner submission package.
Checked 2026-07-15
Article types
Article
Review
Brief Communication
Readiness requirements
Review the key details below, or download the complete checklist with every stored source-backed requirement.
Keywords
- Include or confirm the keywords required by the journal. Articlo checks this item and flags anything that still needs author input.
Reference style
- Articlo formats your supplied references to the journal's stored style and checks that citations match the reference list; source validity is not verified.
- Authors must provide details of the conference proceedings paper with their submission including relevant citation in the submitted manuscript.
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- Authors should disclose details of preprint posting, including DOI and licensing terms, upon submission of the manuscript or at any other point during consideration at a Nature Portfolio journal.
Figure and table rules
- Keep every figure and table numbered, captioned, and cited in the manuscript.
- Review: The use of non-generative machine learning tools to manipulate, combine or enhance existing images or figures should be disclosed in the relevant caption upon submission to allow a case-by-case review.
Funding statement
- Include or confirm the funding statement required by the journal. Articlo checks this item and flags anything that still needs author input.
Competing interests
- Include or confirm the competing interests required by the journal. Articlo checks this item and flags anything that still needs author input.
Ethics statement
- Include or confirm the ethics statement required by the journal. Articlo checks this item and flags anything that still needs author input.
Title page and author information
- Include or confirm the title page and author information required by the journal. Articlo checks this item and flags anything that still needs author input.
Preprints and prior publication
- Researchers should be aware however that such coverage may reduce or pre-empt coverage by other media at the time of publication.
- Authors must obtain all necessary permissions to re-use previously published material and attribute appropriately.
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- Article: If your article is accepted for publication (known as Acceptance in Principle ), you will need to follow the formatting guidelines.
Artificial intelligence disclosure
- These AI-assisted improvements may include wording and formatting changes to the texts, but do not include generative editorial work and autonomous content creation.
Other submission requirements
- You will need to log in; if you do not have an account, you will be able to register for one when you submit.
- The use of an LLM (or other AI-tool) for “AI assisted copy editing” purposes does not need to be declared.
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- *All exceptions must be labelled clearly as generated by AI within the image field.
- Review: Manuscripts may also include sensitive or proprietary information that should not be shared outside the peer review process.
- 1 – What you need to know before initial submission.
- © 2026 Springer Nature Limited.
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Submission forms and permissions
- Click ‘Submit manuscript’ and you will be taken to our online submission system, where you can upload the required files and check on the status of your manuscript after submission.
Manuscript structure
- Use of an LLM should be properly documented in the Methods section (and if a Methods section is not available, in a suitable alternative part) of the manuscript.
- However, the submission should provide a substantial extension of results, methodology, analysis, conclusions and/or implications over the conference proceedings paper; the final decision on what constitutes a substantial extension is made by the editors at each individual journal.
Authorship and originality
- In all cases, there must be human accountability for the final version of the text and agreement from the authors that the edits reflect their original work.
- AI authorship Large Language Models (LLMs), such as ChatGPT, do not currently satisfy our authorship criteria.
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- Notably an attribution of authorship carries with it accountability for the work, which cannot be effectively applied to LLMs.
Language and text style
- Accessory content can include (but is not limited to): key points, glossary terms, editorial summaries, plain language summaries and social media posts.
What your package checks
Source transparency
This preparation guide uses published journal-specific author requirements. Journal instructions can change, so authors should complete a final review before submission.
Open official guideline source